Toru Shimizu Selected Research

Antioxidants

3/2015	ABCG2 variant has opposing effects on onset ages of Parkinson's disease and gout.
8/2013	The nuclear factor erythroid 2-related factor 2 activator oltipraz attenuates chronic hypoxia-induced cardiopulmonary alterations in mice.

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Toru Shimizu Research Topics

Disease

22	Gout 03/2021 - 04/2008
6	Hyperuricemia 01/2016 - 04/2012
4	Pulmonary Hypertension 01/2020 - 01/2014
4	Hypoxia (Hypoxemia) 01/2020 - 08/2013
3	Pulmonary Arterial Hypertension 01/2019 - 12/2013
3	Fibrosis (Cirrhosis) 07/2017 - 01/2014
2	Coronary Artery Disease (Coronary Atherosclerosis) 12/2019 - 01/2013
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2019 - 01/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 06/2016 - 12/2013
2	Hypertrophy 06/2014 - 01/2014
2	Hearing Loss (Hearing Impairment) 01/2008 - 11/2006
1	Fistula 02/2022
1	Aspiration Pneumonia 02/2022
1	Portal Hypertension 01/2021
1	Biliary Atresia 01/2021
1	Heart Failure 01/2020
1	Pathologic Processes 12/2019
1	Myocardial Infarction 12/2019
1	Pulmonary Veno-Occlusive Disease (Veno Occlusive Disease, Pulmonary) 01/2019
1	Pulmonary Edema 01/2019
1	Melanoma (Melanoma, Malignant) 12/2018
1	Virus Diseases (Viral Diseases) 11/2018
1	Cardiomegaly (Heart Hypertrophy) 07/2017
1	Left Ventricular Dysfunction 07/2017
1	Phantom Limb (Phantom Limbs) 01/2017
1	Neuralgia (Stump Neuralgia) 01/2017
1	Thrombosis (Thrombus) 01/2017
1	Pain (Aches) 01/2017
1	Causalgia (Syndrome, Causalgia) 01/2017
1	Diabetes Mellitus 04/2016
1	Renal hypouricemia 01/2016
1	Arrhythmogenic Right Ventricular Dysplasia (Arrhythmogenic Right Ventricular Cardiomyopathy) 10/2015
1	Sudden Death 10/2015
1	Parkinson Disease (Parkinson's Disease) 03/2015
1	Inflammation (Inflammations) 09/2014
1	Right Ventricular Hypertrophy 06/2014
1	Joint Instability (Joint Laxity) 01/2014
1	Hypercholesterolemia 01/2014
1	Body Weight (Weight, Body) 01/2014
1	Wounds and Injuries (Trauma) 01/2014

Drug/Important Bio-Agent (IBA)

19	Uric Acid (Urate)IBA 03/2021 - 04/2008
5	Proteins (Proteins, Gene)FDA Link 01/2015 - 08/2012
4	urate transporterIBA 01/2017 - 01/2013
4	rho-Associated KinasesIBA 10/2015 - 12/2013
3	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2013
3	Heme (Haem)IBA 12/2019 - 04/2011
3	fasudil (AT 877)IBA 06/2016 - 01/2014
2	Cyclophilin AIBA 01/2020 - 01/2013
2	ORALIT (ORS)IBA 10/2019 - 04/2016
2	Glucose (Dextrose)FDA LinkGeneric 04/2016 - 01/2014
2	AntioxidantsIBA 03/2015 - 08/2013
2	Phosphotransferases (Kinase)IBA 12/2011 - 04/2011
2	GlobinsIBA 12/2011 - 04/2011
2	Peptide Initiation Factors (Initiation Factor)IBA 12/2011 - 04/2011
1	SolutionsIBA 02/2022
1	Therapeutic UsesIBA 01/2020
1	Natriuretic PeptidesIBA 01/2020
1	TroponinIBA 01/2020
1	Complement Factor D (Factor D)IBA 12/2019
1	Vasodilator Agents (Vasodilators)IBA 01/2019
1	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2019
1	Tyrosine Kinase InhibitorsIBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019
1	Imatinib Mesylate (Gleevec)FDA Link 01/2019
1	Phytosterols (Plant Sterols)IBA 12/2018
1	Liposomes (Liposome)IBA 12/2018
1	Poly I-CIBA 11/2018
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 07/2017
1	Angiotensin IIIBA 07/2017
1	Thiopental (Pentothal)FDA Link 01/2017
1	Pentazocine (Talwin)FDA LinkGeneric 01/2017
1	histidylhistidine (His-His)IBA 01/2017
1	glutamyl-glutamic acid (Glu-Glu)IBA 01/2017
1	Tetracaine (Amethocaine)FDA LinkGeneric 01/2017
1	Protein Isoforms (Isoforms)IBA 06/2016
1	Glutamic Acid (Glutamate)FDA Link 04/2016
1	CholesterolIBA 04/2016
1	Intergenic DNA (Junk DNA)IBA 01/2016
1	Myosins (Myosin)IBA 01/2015
1	Protein Kinases (Protein Kinase)IBA 01/2015
1	Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA 09/2014
1	Cyclic GMP-Dependent Protein Kinase Type IIIBA 07/2014
1	LigandsIBA 04/2014
1	rhoA GTP-Binding ProteinIBA 01/2014
1	Leucine (L-Leucine)FDA Link 01/2014
1	IceIBA 01/2014
1	CollagenIBA 01/2014
1	Messenger RNA (mRNA)IBA 01/2014
1	MonocrotalineIBA 01/2014
1	Collagenases (Collagenase)FDA Link 01/2014

Therapy/Procedure

4	Therapeutics 01/2019 - 01/2013
2	Castration 01/2008 - 11/2006
1	Tracheostomy 02/2022
1	Cannula 02/2022
1	Surgical Portasystemic Shunt (Portosystemic Shunt) 01/2021
1	Liver Transplantation 01/2021
1	Patient Readmission 12/2019
1	Length of Stay 01/2017
1	Surgical Amputation (Amputations) 01/2017
1	Appendectomy 01/2017